Intervention: Lumacaftor, Ivacaftor Drug Combination
Found 26 matching trials
A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation
PHASE4
The study will evaluate the impact of smart adherence technology for monito...
Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation
PHASE3
This is a Phase 3, multicenter, open-label and roll-over study in participa...
A Phase 1 Study to Examine the Drug-Drug Interaction of Ciprofloxacin, Itraconazole, and Rifampin on the Combination of Lumacaftor With Ivacaftor in Healthy Adult Subjects
PHASE1
The purpose of this study is to examine the drug-drug interaction effects o...
A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del
PHASE2
This study will explore the impact of lumacaftor/ivacaftor (LUM/IVA) on dis...